Melanotan 1 VS Melanotan 2

Melanotan 1 (MT-1):

• Purpose: Primarily developed for individuals with fair skin to increase melanin production and reduce the risk of skin cancer by providing a protective tan.

• Mechanism: Mimics α-MSH (alpha-melanocyte-stimulating hormone) to stimulate melanin production in the skin, leading to gradual tanning without prolonged sun exposure.

• Potency: Less potent than MT-2, offering a more gradual and subtle tanning effect.

• Side Effects: Fewer side effects compared to MT-2, with minimal impact on appetite, libido, or other physiological processes.

• Common Use: Used primarily in clinical settings for skin conditions like erythropoietic protoporphyria (EPP), a rare sensitivity to light.

Melanotan 2 (MT-2):

• Purpose: Also increases melanin production for a deep tan but is often used recreationally for cosmetic tanning and body enhancement.

• Mechanism: Acts similarly to MT-1 but is more potent and has a broader range of effects due to its interaction with other melanocortin receptors.

• Potency: Stronger and faster results in tanning, often with a darker and longer-lasting tan.

• Side Effects:

  • Increased libido and spontaneous erections (due to interaction with MC4R receptors).

  • Possible nausea, flushing, and appetite suppression.

  • More pronounced side effects compared to MT-1.

• Common Use: Popular in the fitness and bodybuilding community for achieving a darker, more defined tan with minimal sun exposure.

Key Differences:

1. Potency & Speed: MT-2 is stronger and works faster, while MT-1 provides a slower, more natural tan.

2. Side Effects: MT-1 has fewer side effects, while MT-2 may cause libido enhancement, nausea, and appetite changes.

3. Use Cases: MT-1 is used more for medical purposes, while MT-2 is widely used for cosmetic tanning and performance aesthetics.